The Cessna 335 is an unpressurized version, which appears the same externally as the 340. The 335 variant is unpressurized six-seat twin powered by Continental TSIO-520-EB engines of 300hp (225 kW) each.

The Cessna 335 was marketed as a low-priced, non-pressurized, version powered by 300 hp (225 kW) Continental TSIO-520-EB engines. The prototype 335 made its maiden flight on December 5, 1978, with the first production aircraft flying in 1979.